Get Anatomy Skin (Integumen) Epidermis Gif. The epidermis (the uppermost layer of skin) is an important system that creates our skin tone, while the dermis (the middle layer) contains connective tissue, hair follicles, and sweat glands that help regulate the integrity and temperature of our the skin. Skin is the largest organ in the body and covers the body's entire external surface.
The inner layer of the skin, the subcutis, contains fat that protects us from trauma.
The keratinocytes which make up 90% of the epidermis The skin has up to seven layers of ectodermal tissue and guards the underlying muscles, bones. The skin covers the entire external surface of the human body and is the principal site of interaction with the surrounding world. The stratum basale (stratum germinativum) contains a single layer of columnar cells actively dividing by mitosis to produce cells that migrate into the upper epidermal layers and ultimately to the surface of the skin.